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Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Minibody) (CAT#: MiniB-161)
Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Minibody) is designed to be expressed as the anti-FGFR1 scFv fused to N-terminus of Knob-CH3 domain and the anti-KLB scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can bind two factors simultaneously and act as mimetic hormone (FGF21) . It is designed for the research of Type 2 diabetes therapy.
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