Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-IgG) (BSSG-161)

Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-FGFR1 antibody variable domain are respectively connected to the N terminus of the anti-KLB IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can bind two factors simultaneously and act as mimetic hormone (FGF21) . It is designed for the research of Type 2 diabetes therapy.

Datasheet INQUIRY

Specifications

Targets

FGFR1 & KLB

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Type 2 diabetes

Targets

Target 1

FGFR1

Gene ID

2260

UniProt ID

P11362

Alternative Names

FGFR1; fibroblast growth factor receptor 1; CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; basic fibroblast growth factor receptor 1; HBGFR; FMS-like tyrosine kinase 2

Target 2

KLB

Gene ID

152831

UniProt ID

Q86Z14

Alternative Names

klotho beta; BKL; KLB; Beta-klotho; B-klotho; BetaKlotho; klotho beta like 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-IgG) (BSSG-161). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-IgG) (CAT#: BSSG-161)

Specifications

Targets

Customer Reviews and Q&As