Home > Products > FGFR1 & KLB > Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Single-chain Diabody)

Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Single-chain Diabody)  (SCDB-H326)

Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can bind two factors simultaneously and act as mimetic hormone (FGF21) . It is designed for the research of Type 2 diabetes therapy.

Specifications
Targets
FGFR1 & KLB
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
FGFR1
Host Animal 1
Human
Target 2
KLB
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Type 2 diabetes
Targets
Target 1
FGFR1
Gene ID
UniProt ID
Alternative Names
FGFR1; fibroblast growth factor receptor 1; CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; basic fibroblast growth factor receptor 1; HBGFR; FMS-like tyrosine kinase 2
Target 2
KLB
Gene ID
UniProt ID
Alternative Names
klotho beta; BKL; KLB; Beta-klotho; B-klotho; BetaKlotho; klotho beta like 3

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