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Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-162)
Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-FIXa specificity is fused to the C terminus of the anti-FX Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can bind and dimerize two factors. It acts as mimetic FXIII. It is designed for the research of Hemophilia A therapy.
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