Recombinant Human Anti-FIXa x Anti-FX Bispecific Antibody (Fab-IgG) (FABIG-H327)

Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can bind and dimerize two factors. It acts as mimetic FXIII. It is designed for the research of Hemophilia A therapy.

Datasheet INQUIRY

Specifications

Targets

FIXa & FX

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hemophilia A

Targets

Target 1

FIXa

Gene ID

2158

UniProt ID

P00740

Alternative Names

F9; coagulation factor IX; FIX; P19; PTC; HEMB; THPH8; F9 p22; FIX F9; factor 9; factor IX F9; Christmas factor; plasma thromboplastic component; plasma thromboplastin component

Target 2

Gene ID

2159

UniProt ID

P00742

Alternative Names

F10; coagulation factor X; FX; FXA; factor Xa; prothrombinase; Stuart-Prower factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-FIXa x Anti-FX Bispecific Antibody (Fab-IgG) (CAT#: FABIG-H327)

Specifications

Targets

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