Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-FIXa IgG with similar domains from an anti-FX antibody via short peptide linkers, or vice versa. This BsAb can bind and dimerize two factors. It acts as mimetic FXIII. It is designed for the research of Hemophilia A therapy.
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