Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (IgG-Fv) (BSGV-162)

Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-FIXa antibody variable domain is fused to the C terminal of an IgG of anti-FX antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can bind and dimerize two factors. It acts as mimetic FXIII. It is designed for the research of Hemophilia A therapy.

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Specifications

Targets

FIXa & FX

Type

IgG-Fv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hemophilia A

Targets

Target 1

FIXa

Gene ID

2158

UniProt ID

P00740

Alternative Names

F9; coagulation factor IX; FIX; P19; PTC; HEMB; THPH8; F9 p22; FIX F9; factor 9; factor IX F9; Christmas factor; plasma thromboplastic component; plasma thromboplastin component

Target 2

Gene ID

2159

UniProt ID

P00742

Alternative Names

F10; coagulation factor X; FX; FXA; factor Xa; prothrombinase; Stuart-Prower factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (IgG-Fv) (CAT#: BSGV-162)

Specifications

Targets

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