Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Single-chain Diabody) (SCDB-162)

Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can bind and dimerize two factors. It acts as mimetic FXIII. It is designed for the research of Hemophilia A therapy.

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Specifications

Targets

FIXa & FX

Type

Single-chain Diabody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hemophilia A

Targets

Target 1

FIXa

Gene ID

2158

UniProt ID

P00740

Alternative Names

F9; coagulation factor IX; FIX; P19; PTC; HEMB; THPH8; F9 p22; FIX F9; factor 9; factor IX F9; Christmas factor; plasma thromboplastic component; plasma thromboplastin component

Target 2

Gene ID

2159

UniProt ID

P00742

Alternative Names

F10; coagulation factor X; FX; FXA; factor Xa; prothrombinase; Stuart-Prower factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Single-chain Diabody) (CAT#: SCDB-162)

Specifications

Targets

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