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Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Tandem Fab)  (BSFAB-162)

Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-FIXa and anti-FX parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can bind and dimerize two factors. It acts as mimetic FXIII. It is designed for the research of Hemophilia A therapy.

Specifications

Targets
FIXa & FX
Type
Tandem Fab
Species Reactivity
Human
Target 1
FIXa
Host Animal 1
Mouse
Target 2
FX
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Hemophilia A

Targets

Target 1
FIXa
Gene ID
UniProt ID
Alternative Names
F9; coagulation factor IX; FIX; P19; PTC; HEMB; THPH8; F9 p22; FIX F9; factor 9; factor IX F9; Christmas factor; plasma thromboplastic component; plasma thromboplastin component
Target 2
FX
Gene ID
UniProt ID
Alternative Names
F10; coagulation factor X; FX; FXA; factor Xa; prothrombinase; Stuart-Prower factor

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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