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Recombinant Human Anti-FN1 x Human Anti-HSG Bispecific Antibody (scFv-Fc)  (BSCFV-H329)

Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-FN1 specificity or anti-HSG specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Solid tumors imaging and therapy.

Specifications

Targets
FN1 & HSG
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
FN1
Host Animal 1
Mouse
Target 2
HSG
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Solid tumors

Targets

Target 1
FN1
Gene ID
UniProt ID
Alternative Names
FN1; fibronectin 1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; Cold-insoluble globulin; Migration-stimulating factor
Target 2
HSG
Alternative Names
histaminyl-succinyl-glycine; HSG

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