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Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (scFv4-Ig)  (CAT#: FVTIG-163)

Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-FN1 scFv is fused to the CH1 domain of a heavy chain and another anti-HSG scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Solid tumors imaging and therapy.
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Specifications

Targets
FN1 & HSG
Type
Appended IgGs
Species Reactivity
Human
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Solid tumors

Targets

Target 1
FN1
Gene ID
UniProt ID
Alternative Names
FN1; fibronectin 1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; Cold-insoluble globulin; Migration-stimulating factor
Target 2
HSG
Alternative Names
histaminyl-succinyl-glycine; HSG
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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