Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Diabody-CH3) (BSDBC-164)

Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-gp40 and anti-TFRC antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can bind two tumor antigens simultaneously. It is designed for the research of Colon cancer; Ovarian cancer therapy.

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Specifications

Targets

gp40 & TFRC

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colon cancer; Ovarian cancer

Targets

Target 1

gp40

Alternative Names

gp40; glycoprotein 40; adenocarcinoma-associated antigen

Target 2

TFRC

Gene ID

7037

UniProt ID

P02786

Alternative Names

TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71); IMD46

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-164)

Specifications

Targets

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