Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (F(ab')2-scFv2) (BABFV-164)

Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-gp40 specificity is fused to the C terminus of the anti-TFRC Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can bind two tumor antigens simultaneously. It is designed for the research of Colon cancer; Ovarian cancer therapy.

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Specifications

Targets

gp40 & TFRC

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colon cancer; Ovarian cancer

Targets

Target 1

gp40

Alternative Names

gp40; glycoprotein 40; adenocarcinoma-associated antigen

Target 2

TFRC

Gene ID

7037

UniProt ID

P02786

Alternative Names

TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71); IMD46

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-164)

Specifications

Targets

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