Name: Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Fab-scFv-Fc)
SKU: FABVC-164
Rating: 5 (1 reviews)

Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-gp40 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-TFRC to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can bind two tumor antigens simultaneously. It is designed for the research of Colon cancer; Ovarian cancer therapy.

Datasheet INQUIRY

Specifications

Targets

gp40 & TFRC

Type

Fab-scFv/sdAb-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colon cancer; Ovarian cancer

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

gp40

Alternative Names

gp40; glycoprotein 40; adenocarcinoma-associated antigen

Target 2

TFRC

Gene ID

7037

UniProt ID

P02786

Alternative Names

TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71); IMD46

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-164)

Specifications

Targets

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