Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (IgG(L)-scFv) (IGLFV-164)

Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-gp40 antibody are fused to the C terminus of an anti-TFRC IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can bind two tumor antigens simultaneously. It is designed for the research of Colon cancer; Ovarian cancer therapy.

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Specifications

Targets

gp40 & TFRC

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colon cancer; Ovarian cancer

Targets

Target 1

gp40

Alternative Names

gp40; glycoprotein 40; adenocarcinoma-associated antigen

Target 2

TFRC

Gene ID

7037

UniProt ID

P02786

Alternative Names

TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71); IMD46

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-164)

Specifications

Targets

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