Home > Products > gp40 & TFRC > Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scDiabody-CH3)

Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scDiabody-CH3)  (SCDBC-164)

Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-gp40/anti-TFRC diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can bind two tumor antigens simultaneously. It is designed for the research of Colon cancer; Ovarian cancer therapy.

Specifications
Targets
gp40 & TFRC
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
gp40
Host Animal 1
Mouse
Target 2
TFRC
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Colon cancer; Ovarian cancer
Targets
Target 1
gp40
Alternative Names
gp40; glycoprotein 40; adenocarcinoma-associated antigen
Target 2
TFRC
Gene ID
UniProt ID
Alternative Names
TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71); IMD46

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