Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-gp40 antibody variable domain is fused to CH1 and the other scFv from an anti-TFRC antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can bind two tumor antigens simultaneously. It is designed for the research of Colon cancer; Ovarian cancer therapy.
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