Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-CH3) (BSFC-164)

Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-CH3) contains two chains. The anti-gp40 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-TFRC scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind two tumor antigens simultaneously. It is designed for the research of Colon cancer; Ovarian cancer therapy.

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Specifications

Targets

gp40 & TFRC

Type

scFv-CH3

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colon cancer; Ovarian cancer

Targets

Target 1

gp40

Alternative Names

gp40; glycoprotein 40; adenocarcinoma-associated antigen

Target 2

TFRC

Gene ID

7037

UniProt ID

P02786

Alternative Names

TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71); IMD46

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-CH3) (CAT#: BSFC-164)

Specifications

Targets

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