Name: Recombinan Human Anti-HER2 x Human Anti-Vγ9 Bispecific Antibody (Fab-scFv-scFv)
SKU: KN-0825-N67
Rating: 5 (1 reviews)

Recombinan Human Anti-HER2 x Human Anti-Vγ9 Bispecific Antibody (Fab-scFv-scFv) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-Vγ9 antibody are both extended with the scFv fragment from an anti-HER2 antibody. This BsAb can retarget γδ T cells to HER2+ tumor cells . It is designed for the research of Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

HER2 & Vγ9

Type

Fab-scFv-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors

Host Animal 1

Human

Host Animal 2

Human

Targets

Target 1

HER2

Gene ID

2064

UniProt ID

P04626

Alternative Names

ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

Target 2

Vγ9

Gene ID

6983

UniProt ID

Q99603

Alternative Names

Vgamma9Vdelta2; TCR γ-chain; γ9 subunit of Vγ9Vδ2 TCR complex; High-affinity Vγ9-containing TCR; TRGV9; T cell receptor gamma variable 9; V2; TRGC1; TCRGV9

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

See other bsAb targets related to "HER2"

See other bsAb targets related to "Vγ9"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinan Human Anti-HER2 x Human Anti-Vγ9 Bispecific Antibody (Fab-scFv-scFv) (KN-0825-N67). Click the button below to contact us or submit your feedback about this product.

Recombinan Human Anti-HER2 x Human Anti-Vγ9 Bispecific Antibody (Fab-scFv-scFv) (CAT#: KN-0825-N67)

Specifications

Targets

Customer Reviews and Q&As