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Recombinant Anti-HER2 x Anti-VEGF Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-168)
Recombinant Anti-HER2 x Anti-VEGF Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-HER2 antibody are fused to the C terminus of an anti-VEGF IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can bind two factors simultaneously and inhibit cell proliferation. It is designed for the research of Colorectal cancer; Breast cancer; Lung cancer; Renal cell cancer (RCC); Glioma cancer; Glioblastoma; Ovarian cancer therapy.
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