Recombinant Anti-HER3 x Anti-IGF1R Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-HER3/anti-IGF1R diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Pancreatic cancer; Hepatocellular carcinoma (HCC) therapy.
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