Home > Products > HIV-1 gp41 & CD89 > Recombinant Anti-HIV-1 gp41 x Anti-CD89 Bispecific Antibody (Single-chain Triplebody)

Recombinant Anti-HIV-1 gp41 x Anti-CD89 Bispecific Antibody (Single-chain Triplebody)  (SCTB-H195)

Recombinant Anti-HIV-1 gp41 x Anti-CD89 Bispecific Antibody (Single-chain Triplebody) is designed to be expressed as a single chain with three scFv units, two distal binding sites for HIV-1 gp41 and a central site for CD89 . It contains a His-tag at the C/N terminus for affinity purification. This BsAb can retarget macrophages to HIV-1 infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.

Specifications
Targets
HIV-1 gp41 & CD89
Type
Single-chain Triplebody
Species Reactivity
Human
Target 1
HIV-1 gp41
Host Animal 1
Human
Target 2
CD89
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
HIV-1 infection, AIDS
Targets
Target 1
HIV-1 gp41
Gene ID
UniProt ID
Alternative Names
ENV; gp160; Envelope glycoprotein 120; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; human immunodeficiency virus type 1; human immunodeficiency virus type 1 gp120; human immunodeficiency virus type 1 glycoprotein 120; gp41; GP41; glycoprotein 41
Target 2
CD89
Gene ID
UniProt ID
Alternative Names
FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor
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