Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Tandem scFv-Fc) (BSFVF-H335)

Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-HSG/TROP2 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Pancreatic cancer; Breast cancer; Gastrointestinal cancer; Cancers imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

HSG & TROP2

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Pancreatic cancer; Breast cancer; Gastrointestinal cancer; Cancers

Targets

Target 1

HSG

Alternative Names

histaminyl-succinyl-glycine; HSG

Target 2

TROP2

Gene ID

4070

UniProt ID

P09758

Alternative Names

TACSTD2; tumor-associated calcium signal transducer 2; EGP1; GP50; M1S1; EGP-1; TROP2; Trop-2; GA7331; GA733-1; epithelial glycoprotein-1; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; gastrointestinal tumor-associated antigen GA7331; membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; 40kD glycoprotein, identified by monoclonal antibody GA733

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Tandem scFv-Fc) (CAT#: BSFVF-H335)

Specifications

Targets

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