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Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-177)
Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-IL1α antibody are fused to the C terminus of an anti-IL1β IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.
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