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Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (Miniantibody)  (CAT#: MNAB-177)

Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-IL1α antibody variable domain is linked to another scFv of an anti-IL1β antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.
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Specifications

Targets
IL1α & IL1β
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Osteoarthritis (OA)

Targets

Target 1
IL1α
Gene ID
UniProt ID
Alternative Names
IL1; IL-1A; IL1F1; IL1-ALPHA; Interleukin 1 alpha; hematopoietin 1; IL1α
Target 2
IL1β
Gene ID
UniProt ID
Alternative Names
IL-1; IL1F2; IL1-BETA; IL1β; Interleukin-1β; IL-1β
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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