Home > Products > IL1α & IL1β > Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (Minibody)

Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (Minibody)  (MiniB-177)

Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (Minibody) is designed to be expressed as the anti-IL1α scFv fused to N-terminus of Knob-CH3 domain and the anti-IL1β scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.

Specifications

Targets
IL1α & IL1β
Type
Minibody
Species Reactivity
Human
Target 1
IL1α
Host Animal 1
Mouse
Target 2
IL1β
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Osteoarthritis (OA)

Targets

Target 1
IL1α
Gene ID
UniProt ID
Alternative Names
IL1; IL-1A; IL1F1; IL1-ALPHA; Interleukin 1 alpha; hematopoietin 1; IL1α
Target 2
IL1β
Gene ID
UniProt ID
Alternative Names
IL-1; IL1F2; IL1-BETA; IL1β; Interleukin-1β; IL-1β

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