Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-IL1α and anti-IL1β parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.
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