Home > Products > IL12 & IL18 > Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (F(ab')2-scFv2)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (F(ab')2-scFv2)  (BABFV-171)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-IL12 specificity is fused to the C terminus of the anti-IL18 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Arthritis therapy.

Specifications
Targets
IL12 & IL18
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
IL12
Host Animal 1
Mouse
Target 2
IL18
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Arthritis
Targets
Target 1
IL12
Gene ID
UniProt ID
Alternative Names
P35; CLMF; NFSK; NKSF1; IL-12A; IL12; IL-12; interleukin 12A
Target 2
IL18
Gene ID
UniProt ID
Alternative Names
IGIF; IL-18; IL-1g; IL1F4; interleukin 18; IL18
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