Recombinant Human Anti-IL12 x Human Anti-IL18 Bispecific Antibody (Fab-Fv) (FABFV-H336)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-IL12 antibody are fused with the VL and VH domains of an anti-IL18 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Arthritis therapy.

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Specifications

Targets

IL12 & IL18

Type

Fab-Fv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Arthritis

Targets

Target 1

IL12

Gene ID

3592

UniProt ID

P29459

Alternative Names

P35; CLMF; NFSK; NKSF1; IL-12A; IL12; IL-12; interleukin 12A

Target 2

IL18

Gene ID

3606

UniProt ID

A0A024R3E0

Alternative Names

IGIF; IL-18; IL-1g; IL1F4; interleukin 18; IL18

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL12 x Human Anti-IL18 Bispecific Antibody (Fab-Fv) (CAT#: FABFV-H336)

Specifications

Targets

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