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Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (scFv-CH1/CL)  (CAT#: BSCC-171)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-IL12 antibody variable domain is fused to CH1 and the other scFv from an anti-IL18 antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Arthritis therapy.
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Specifications

Targets
IL12 & IL18
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Arthritis

Targets

Target 1
IL12
Gene ID
UniProt ID
Alternative Names
P35; CLMF; NFSK; NKSF1; IL-12A; IL12; IL-12; interleukin 12A
Target 2
IL18
Gene ID
UniProt ID
Alternative Names
IGIF; IL-18; IL-1g; IL1F4; interleukin 18; IL18
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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