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Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (scFv-Fc)  (CAT#: BSCFV-171)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-IL12 specificity or anti-IL18 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Arthritis therapy.
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Specifications

Targets
IL12 & IL18
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Arthritis

Targets

Target 1
IL12
Gene ID
UniProt ID
Alternative Names
P35; CLMF; NFSK; NKSF1; IL-12A; IL12; IL-12; interleukin 12A
Target 2
IL18
Gene ID
UniProt ID
Alternative Names
IGIF; IL-18; IL-1g; IL1F4; interleukin 18; IL18
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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