Recombinant Human Anti-IL12 x Human Anti-IL18 Bispecific Antibody (scFv4-Ig) (FVTIG-H336)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-IL12 scFv is fused to the CH1 domain of a heavy chain and another anti-IL18 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Arthritis therapy.

Datasheet INQUIRY

Specifications

Targets

IL12 & IL18

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Arthritis

Targets

Target 1

IL12

Gene ID

3592

UniProt ID

P29459

Alternative Names

P35; CLMF; NFSK; NKSF1; IL-12A; IL12; IL-12; interleukin 12A

Target 2

IL18

Gene ID

3606

UniProt ID

A0A024R3E0

Alternative Names

IGIF; IL-18; IL-1g; IL1F4; interleukin 18; IL18

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL12 x Human Anti-IL18 Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-H336)

Specifications

Targets

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