Home > Products > IL12 & IL18 > Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (Tandem Fab)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (Tandem Fab)  (BSFAB-171)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-IL12 and anti-IL18 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Arthritis therapy.

Specifications

Targets
IL12 & IL18
Type
Tandem Fab
Species Reactivity
Human
Target 1
IL12
Host Animal 1
Mouse
Target 2
IL18
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Arthritis

Targets

Target 1
IL12
Gene ID
UniProt ID
Alternative Names
P35; CLMF; NFSK; NKSF1; IL-12A; IL12; IL-12; interleukin 12A
Target 2
IL18
Gene ID
UniProt ID
Alternative Names
IGIF; IL-18; IL-1g; IL1F4; interleukin 18; IL18

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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