Home > Products > IL13 & IL17 > Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (scFv-Fc-scFv)

Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (scFv-Fc-scFv)  (BSTF-H337)

Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-IL13 scFv is fused to the N-terminus of Fc via a hinge region while another anti-IL17 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Asthma therapy.

Specifications
Targets
IL13 & IL17
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
IL13
Host Animal 1
Mouse
Target 2
IL17
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Asthma
Targets
Target 1
IL13
Gene ID
UniProt ID
Alternative Names
IL13; interleukin 13; P600; IL-13; interleukin-13
Target 2
IL17
Gene ID
UniProt ID
Alternative Names
IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
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