Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody-CH3) (BSDBC-173)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-IL13 and anti-IL4 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Idiopathic pulmonary fibrosis therapy.

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Specifications

Targets

IL13 & IL4

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Idiopathic pulmonary fibrosis

Targets

Target 1

IL13

Gene ID

3596

UniProt ID

P35225

Alternative Names

IL13; interleukin 13; P600; IL-13; interleukin-13

Target 2

IL4

Gene ID

3565

UniProt ID

D4HNR6

Alternative Names

IL4; interleukin 4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; interleukin 4 variant 2; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-173)

Specifications

Targets

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