Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-IgG) (FABIG-H337)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Idiopathic pulmonary fibrosis therapy.

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Specifications

Targets

IL13 & IL4

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Idiopathic pulmonary fibrosis

Targets

Target 1

IL13

Gene ID

3596

UniProt ID

P35225

Alternative Names

IL13; interleukin 13; P600; IL-13; interleukin-13

Target 2

IL4

Gene ID

3565

UniProt ID

D4HNR6

Alternative Names

IL4; interleukin 4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; interleukin 4 variant 2; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-IgG) (CAT#: FABIG-H337)

Specifications

Targets

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