Home > Products > IL13 & IL4 > Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fv-IgG)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fv-IgG)  (BSDG-173)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-IL13 IgG with similar domains from an anti-IL4 antibody via short peptide linkers, or vice versa. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Idiopathic pulmonary fibrosis therapy.

Specifications

Targets
IL13 & IL4
Type
Appended IgGs
Species Reactivity
Human
Target 1
IL13
Host Animal 1
Mouse
Target 2
IL4
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Idiopathic pulmonary fibrosis

Targets

Target 1
IL13
Gene ID
UniProt ID
Alternative Names
IL13; interleukin 13; P600; IL-13; interleukin-13
Target 2
IL4
Gene ID
UniProt ID
Alternative Names
IL4; interleukin 4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; interleukin 4 variant 2; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1

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