Name: Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG(L)-scFv)
SKU: IGLFV-173
Rating: 5 (1 reviews)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-IL13 antibody are fused to the C terminus of an anti-IL4 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Idiopathic pulmonary fibrosis therapy.

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Specifications

Targets

IL13 & IL4

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Idiopathic pulmonary fibrosis

Targets

Target 1

IL13

Gene ID

3596

UniProt ID

P35225

Alternative Names

IL13; interleukin 13; P600; IL-13; interleukin-13

Target 2

IL4

Gene ID

3565

UniProt ID

D4HNR6

Alternative Names

IL4; interleukin 4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; interleukin 4 variant 2; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-173)

Specifications

Targets

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