Home > Products > IL13 & IL4 > Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (IgG(L)-scFv)

Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (IgG(L)-scFv)  (IGLFV-H338)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-IL13 antibody are fused to the C terminus of an anti-IL4 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Idiopathic pulmonary fibrosis therapy.

Specifications

Targets
IL13 & IL4
Type
Appended IgGs
Species Reactivity
Human
Target 1
IL13
Host Animal 1
Human
Target 2
IL4
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Idiopathic pulmonary fibrosis

Targets

Target 1
IL13
Gene ID
UniProt ID
Alternative Names
IL13; interleukin 13; P600; IL-13; interleukin-13
Target 2
IL4
Gene ID
UniProt ID
Alternative Names
IL4; interleukin 4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; interleukin 4 variant 2; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1

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