Home > Products > IL13 & IL4 > Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-CH3)

Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-CH3)  (BSFC-H338)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-CH3) contains two chains. The anti-IL13 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-IL4 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Idiopathic pulmonary fibrosis therapy.

Specifications

Targets
IL13 & IL4
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
IL13
Host Animal 1
Mouse
Target 2
IL4
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Idiopathic pulmonary fibrosis

Targets

Target 1
IL13
Gene ID
UniProt ID
Alternative Names
IL13; interleukin 13; P600; IL-13; interleukin-13
Target 2
IL4
Gene ID
UniProt ID
Alternative Names
IL4; interleukin 4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; interleukin 4 variant 2; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1

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