Home > Products > IL13 & IL4 > Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv-Fc)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv-Fc)  (BSFVF-173)

Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-IL13/IL4 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Idiopathic pulmonary fibrosis therapy.

Specifications

Targets
IL13 & IL4
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
IL13
Host Animal 1
Mouse
Target 2
IL4
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Idiopathic pulmonary fibrosis

Targets

Target 1
IL13
Gene ID
UniProt ID
Alternative Names
IL13; interleukin 13; P600; IL-13; interleukin-13
Target 2
IL4
Gene ID
UniProt ID
Alternative Names
IL4; interleukin 4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; interleukin 4 variant 2; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1

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