Name: Recombinant Anti-IL17 x Anti-IL23 Bispecific Antibody (Diabody-CH3)
SKU: BSDBC-174
Rating: 5 (1 reviews)

Recombinant Anti-IL17 x Anti-IL23 Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-IL17 and anti-IL23 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Autoimmune diseases; Cancers therapy.

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Specifications

Targets

IL17 & IL23

Type

Diabody-CH3

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Autoimmune diseases; Cancers

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

IL17

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Target 2

IL23

Gene ID

51561

UniProt ID

Q9NPF7

Alternative Names

P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23; IL23; interleukin 23 subunit alpha

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL17 x Anti-IL23 Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-174)

Specifications

Targets

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