Home > Products > IL17 & IL23 > Recombinant Anti-IL17 x Anti-IL23 Bispecific Antibody (Diabody-CH3)

Recombinant Anti-IL17 x Anti-IL23 Bispecific Antibody (Diabody-CH3)  (BSDBC-174)

Recombinant Anti-IL17 x Anti-IL23 Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-IL17 and anti-IL23 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Autoimmune diseases; Cancers therapy.

Specifications

Targets
IL17 & IL23
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
IL17
Host Animal 1
Mouse
Target 2
IL23
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Autoimmune diseases; Cancers

Targets

Target 1
IL17
Gene ID
UniProt ID
Alternative Names
IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Target 2
IL23
Gene ID
UniProt ID
Alternative Names
P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23; IL23; interleukin 23 subunit alpha

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