Recombinant Human Anti-IL17 x Human Anti-IL23 Bispecific Antibody (Fab-scFv-Fc) (FABVC-H339)

Recombinant Anti-IL17 x Anti-IL23 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-IL17 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-IL23 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Autoimmune diseases; Cancers therapy.

Datasheet INQUIRY

Specifications

Targets

IL17 & IL23

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Autoimmune diseases; Cancers

Targets

Target 1

IL17

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Target 2

IL23

Gene ID

51561

UniProt ID

Q9NPF7

Alternative Names

P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23; IL23; interleukin 23 subunit alpha

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL17 x Human Anti-IL23 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-H339)

Specifications

Targets

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