Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (IgG-Fv) (BSGV-H340)

Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-IL17 antibody variable domain is fused to the C terminal of an IgG of anti-TNF antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Rheumatoid arthritis (RA); Plaque psoriasis therapy.

Datasheet INQUIRY

Specifications

Targets

IL17 & TNF

Type

IgG-Fv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Rheumatoid arthritis (RA); Plaque psoriasis

Targets

Target 1

IL17

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Target 2

TNF

Gene ID

7124

UniProt ID

P01375

Alternative Names

TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (IgG-Fv) (CAT#: BSGV-H340)

Specifications

Targets

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