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Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (Miniantibody)  (CAT#: MNAB-H340)

Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-IL17 antibody variable domain is linked to another scFv of an anti-TNF antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Rheumatoid arthritis (RA); Plaque psoriasis therapy.
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Specifications

Targets
IL17 & TNF
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Rheumatoid arthritis (RA); Plaque psoriasis

Targets

Target 1
IL17
Gene ID
3605
UniProt ID
Q16552
Alternative Names
IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Target 2
TNF
Gene ID
7124
UniProt ID
P01375
Alternative Names
TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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