Home > Products > IL17A & IL17F > Recombinant Human Anti-IL17A x Human Anti-IL17F Bispecific Antibody (Diabody-CH3)

Recombinant Human Anti-IL17A x Human Anti-IL17F Bispecific Antibody (Diabody-CH3)  (BSDBC-H341)

Recombinant Anti-IL17A x Anti-IL17F Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-IL17A and anti-IL17F antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Multiple sclerosis (MS); Autoimmune diseases; Inflammatory diseases therapy.

Specifications

Targets
IL17A & IL17F
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
IL17A
Host Animal 1
Human
Target 2
IL17F
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Multiple sclerosis (MS); Autoimmune diseases; Inflammatory diseases

Targets

Target 1
IL17A
Gene ID
UniProt ID
Alternative Names
IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Target 2
IL17F
Gene ID
UniProt ID
Alternative Names
IL17; Interleukin 17; IL17F; Interleukin 17F; ML1; ML-1; CANDF6; IL-17F; cytokine ML-1

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