Recombinant Anti-IL17A x Anti-IL17F Bispecific Antibody (F(ab')2-scFv2) (BABFV-176)

Recombinant Anti-IL17A x Anti-IL17F Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-IL17A specificity is fused to the C terminus of the anti-IL17F Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Multiple sclerosis (MS); Autoimmune diseases; Inflammatory diseases therapy.

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Specifications

Targets

IL17A & IL17F

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple sclerosis (MS); Autoimmune diseases; Inflammatory diseases

Targets

Target 1

IL17A

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Target 2

IL17F

Gene ID

112744

UniProt ID

Q96PD4

Alternative Names

IL17; Interleukin 17; IL17F; Interleukin 17F; ML1; ML-1; CANDF6; IL-17F; cytokine ML-1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL17A x Anti-IL17F Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-176)

Specifications

Targets

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