Recombinant Anti-IL17A x Anti-IL17F Bispecific Antibody (Fab-IgG) (FABIG-176)

Recombinant Anti-IL17A x Anti-IL17F Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Multiple sclerosis (MS); Autoimmune diseases; Inflammatory diseases therapy.

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Specifications

Targets

IL17A & IL17F

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple sclerosis (MS); Autoimmune diseases; Inflammatory diseases

Targets

Target 1

IL17A

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Target 2

IL17F

Gene ID

112744

UniProt ID

Q96PD4

Alternative Names

IL17; Interleukin 17; IL17F; Interleukin 17F; ML1; ML-1; CANDF6; IL-17F; cytokine ML-1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL17A x Anti-IL17F Bispecific Antibody (Fab-IgG) (CAT#: FABIG-176)

Specifications

Targets

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