Recombinant Human Anti-IL17A x Human Anti-IL17F Bispecific Antibody (Tandem scFv-Fc) (BSFVF-H341)

Recombinant Anti-IL17A x Anti-IL17F Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-IL17A/IL17F tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Multiple sclerosis (MS); Autoimmune diseases; Inflammatory diseases therapy.

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Specifications

Targets

IL17A & IL17F

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple sclerosis (MS); Autoimmune diseases; Inflammatory diseases

Targets

Target 1

IL17A

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Target 2

IL17F

Gene ID

112744

UniProt ID

Q96PD4

Alternative Names

IL17; Interleukin 17; IL17F; Interleukin 17F; ML1; ML-1; CANDF6; IL-17F; cytokine ML-1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL17A x Human Anti-IL17F Bispecific Antibody (Tandem scFv-Fc) (CAT#: BSFVF-H341)

Specifications

Targets

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