Recombinant Human Anti-IL23 x Human Anti-IL6 Bispecific Antibody (Diabody-CH3) (BSDBC-H343)

Recombinant Anti-IL23 x Anti-IL6 Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-IL23 and anti-IL6 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Inflammatory diseases therapy.

Datasheet INQUIRY

Specifications

Targets

IL23 & IL6

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Inflammatory diseases

Targets

Target 1

IL23

Gene ID

51561

UniProt ID

Q9NPF7

Alternative Names

P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23; IL23; interleukin 23 subunit alpha

Target 2

IL6

Gene ID

3569

UniProt ID

P05231

Alternative Names

CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; interleukin 6; IL6

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL23 x Human Anti-IL6 Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-H343)

Specifications

Targets

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